Abstract
Hyperprolactinemia with galactorrhea is a well-documented adverse effect of some psychotropic
medications. While advanced practice psychiatric nurses are likely familiar with hyperprolactinemia
with galactorrhea as an adverse effect of antipsychotics, they may be less familiar
with hyperprolactinemia with galactorrhea associated with antidepressants, an adverse
effect that is far less common. Advanced practice psychiatric nurses must be able
to identify hyperprolactinemia and galactorrhea in patients and must be able to evaluate
and manage antidepressant-related hyperprolactinemia with galactorrhea. Thus, this
case report describes hyperprolactinemia with galactorrhea in a teenage female prescribed
venlafaxine for the treatment of major depressive disorder and posttraumatic stress
disorder. To our knowledge, this is the first case report that describes galactorrhea
related to a reuptake inhibitor (SNRI) in an adolescent.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Archives of Psychiatric NursingAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Prevalence and risk factors of hyperprolactinemia among patients with various psychiatric diagnoses and medications.International Journal of Psychiatry in Clinical Practice. 2018; 22: 274-281
- Reversible normoprolactinemic galactorrhea in major depressive disorder with a stable dose of fluoxetine: A case report.Klinik Psikofarmakoloji Bulteni. 2019; 29: 179-180
- Psychotic disorders, definition, sign and symptoms, antipsychotic drugs, mechanism of action, pharmacokinetics & pharmacodynamics with side effects & adverse drug reactions: Updated systematic review article.Journal of Drug Delivery and Therapeutics. 2020; 10: 163-172
- Dose dependent course of hyperprolactinemic and normoprolactinemic galactorrhea induced by venlafaxine.Clinical Psychopharmacology and Neuroscience. 2017; 15: 181
- Correction of normoprolactinemic galactorrhea following treatment with sympathomimetic amines.Fertility and Sterility. 2008; 89: S15
- Prolactin lowering effect of amphetamine in normoprolactinemic subjects and in physiological and pathological hyperprolactinemia.Hormone and Metabolic Research. 1983; 15: 439-443
- Galactorrhea during antipsychotic treatment: Results from AMSP, a drug surveillance program, between 1993 and 2015.European Archives of Psychiatry and Clinical Neuroscience. 2021; 271: 1425-1435
- A case with euprolactinemic galactorrhea induced by escitalopram.The International Journal of Psychiatry in Medicine. 2007; 37: 275-278
- Stress-induced hyperprolactinemia: pathophysiology and clinical approach.Obstetrics and Gynecology International. 2018; 2018
- Aripiprazole for the treatment of duloxetine induced hyperprolactinemia: A case report.Journal of Affective Disorders. 2019; 250: 330-332
- Prolactin lowering and-releasing drugs.Drugs. 1983; 25: 399-432
- Strategies for managing medication-induced hyperprolactinemia.Current Psychiatry. 2018; 17: 42-47
- Galactorrhea associated with sertraline: A case report and literature review.European Psychiatry. 2015; 30: 1
- Galactorrhea and hyperprolactinemia during vortioxetine use: Case report.Turkish Journal of Biochemistry. 2019; 44: 105-107
- Duloxetine associated galactorrhea and hyperprolactinemia: A case report.Turk Psikiyatri Dergisi. 2020; 31: 294
- Hyperprolactinemia: The ABCs of diagnosis and management.Women's Healthcare. 2020;
- Venlafaxine-induced galactorrhea.Journal of Clinical Psychopharmacology. 2003; 23: 109-110
- Galactorrhea with antidepressants: A case series.Indian Journal of Psychiatry. 2018; 60: 145
- Pitfalls in the diagnostic evaluation of hyperprolactinemia.Neuroendocrinology. 2019; 109: 7-19
- Venlafaxine-associated euprolactinemic galactorrhea and hypersexuality: A case report and review of the literature.Journal of Clinical Psychopharmacology. 2016; 36: 399-400
- A case of venlafaxine-induced galactorrhea?.Journal of Clinical Psychopharmacology. 2008; 28: 580-581
Article info
Publication history
Published online: June 04, 2022
Accepted:
June 1,
2022
Received:
April 2,
2022
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.